Boston researchers have for the first time used a drug to regenerate the delicate hair cells that sense sound in the ears of adult mice, in a promising initial step toward a potential treatment for hearing loss.
Hair cells damaged by loud noises or lost during aging don’t regrow in people, but in the mouse experiments published Wednesday, the scientists coaxed new cells to develop, enabling the animals to recover modest hearing.
The deaf mice were far from cured; the improvement in hearing was much less than could be achieved by an existing technology, called a cochlear implant. But researchers not involved in the work said the results, published Wednesday in the journal Neuron, were important because they showed such regeneration was possible and suggested a similar non-surgical approach could one day be tested in people.
“What’s really novel is that they showed you can use a pharmacological reagent, basically a drug, to get some level of hearing recovery in animals in which they’ve lost their hearing because of exposure to loud noise,” said Matthew Kelley, chief of the laboratory of cochlear development at the National Institute on Deafness and other Communication Disorders.
The Limping Chicken is the world's most popular Deaf blog, and is edited by Deaf journalist and filmmaker Charlie Swinbourne.
The site exists thanks to our supporters. Check them out below:
- Signature: Leading awarding body for BSL qualifications
- Ai-Media: Remote captioning. Find out 7 things deaf people want you to know!
- Bellman & Symfon: home alerting solutions
- Deaf Umbrella: sign language interpreting and communications support
- BSL Zone: TV programmes in BSL for the Deaf community
- Eyewitness Media: TV and film from a Deaf perspective
- Appa: Communication services for Deaf, Deafblind and hard of hearing people
- SignLive: Online video interpreting for Deaf people
- SignVideo: Instant BSL video interpreting online
- 121 Captions: captioning and speech-to-text services
- The National Theatre: Captioned and BSL accessible theatre in London
- Doncaster School for the Deaf: education for Deaf children
- Signworld: Learn BSL online!
- Action Deafness Communications: sign language and Red Dot online video interpreting
- BSLcourses.co.uk: Provider of online BSL courses
- Association of Notetaking Professionals: The professional body representing Electronic and Manual Notetakers
- Sign Solutions: communication support, training and translation
- InterpretersLive: On demand BSL video interpretation
- Hamilton Lodge School in Brighton: education for Deaf children
- Lipspeaker UK: specialist lipspeaking support
- Hearing Choices: Australian hearing aid specialists
- Elmfield School, Bristol: Inclusive education for Deaf pupils
- deafPLUS: BSL advice helpline
- Exeter Deaf Academy: education for Deaf children
- Royal Shakespeare Company: Captioned and BSL interpreted performances (see dates here)
- Royal School for the Deaf, Derby: Residential education for deaf children
- RAD Tax Advice: Tax and Tax Credit info for Deaf people
- Performance Interpreting: BSL interpreting at concerts
- National Deaf Children's Society: The leading charity for deaf children
- Signed Culture: Advocating for BSL access to arts and culture
- SignHealth: healthcare charity for Deaf people
- CJ Interpreting: communication support in BSL
- British Society for Mental Health and Deafness: Promoting positive mental health for deaf people